Last edited by Nigis
Sunday, July 12, 2020 | History

2 edition of Lyotropic liquid crystals as drug delivery systems. found in the catalog.

Lyotropic liquid crystals as drug delivery systems.

Pauline Bridget Geraghty

Lyotropic liquid crystals as drug delivery systems.

by Pauline Bridget Geraghty

  • 189 Want to read
  • 39 Currently reading

Published by University of Manchester in Manchester .
Written in English


Edition Notes

Thesis (Ph.D.), - University of Manchester, Department of Pharmacy.

ContributionsUniversity of Manchester. Department of Pharmacy.
The Physical Object
Pagination260p.
Number of Pages260
ID Numbers
Open LibraryOL17275815M

Liquid Crystals provides information pertinent to the characterization and understanding of the liquid crystalline or ordered fluid. This book presents the important developments in the understanding of liquid crystals. Organized into seven chapters, this book begins with an overview of the various relations between liquid crystals and polymers.   Lyotropic liquid crystal systems in drug delivery. 21 April Download Type: Adobe PDF Lyotropic liquid crystal systems, such as reversed bicontinuous cubic and hexagonal mesophases, are attracting more and more attention because of their unique microstructures and physicochemical properties.

  Triggered Drug Release Using Lyotropic Liquid Crystals as Delivery Vehicles. ,,, DOI: /b N. V. Sautina, K. I. Sitdikova, Yu. G. Galyametdinov. Study of phase transitions in lyotropic liquid-crystal emulsion systems tetraethylene glycol monododecyl ether, water, and vaseline oil by the wetting angle method. Title:Nanoparticles of Lyotropic Liquid Crystals: A Novel Strategy for the Topical Delivery of a Chlorin Derivative for Photodynamic Therapy of Skin Cancer VOLUME: 9 ISSUE: 4 Author(s):Raquel Petrilli, Fabiola S.G. Praca, Aline Regina H. Carollo, Wanessa S.G. Medina, Kleber Thiago de Oliveira, Marcia C.A. Fantini, Maria da Graca P.M.S. Neves, Jose A.S. Cavaleiro, Osvaldo A. Serra, Yassuko.

  The book Self‐Assembled Supramolecular Architectures: Lyotropic Liquid Crystals examines both fundamental and applied aspects of these fascinating systems. LLCs obtained with lipids and in dispersed phases, i.e. phases that form with excess water, are of primary focus in the book including biocompatible systems for potential in drug delivery. This thesis describes lyotropic chromonic liquid crystals (LCLCs) with exotic elastic and viscous properties. The first part of the thesis presents a thorough analysis of the elastic and viscous properties of LCLCs as functions of concentration, temperature and ionic contents, while the second part explores an active nematic system: living liquid crystals, which represent a combination of LCLC.


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Lyotropic liquid crystals as drug delivery systems by Pauline Bridget Geraghty Download PDF EPUB FB2

Introduction. Lyotropic liquid crystal (LLC) systems that commonly consist of amphiphilic molecules and solvents can be classified into lamellar (L α), cubic, hexagonal mesophases, and so recent years, LLC systems have received considerable attention because of their excellent potential as drug by:   The first group of chapters discusses our current fundamental understanding of lyotropic liquid crystals, emphasizing lipid-based systems and rod-like solvent dispersions.

The next group of chapters explores applications, with a focus on drug delivery systems.3/5(1). Among them, lipid-based lyotropic liquid crystals (LLC) or liquid crystalline nanoparticles (LCNPs) are highly ordered, thermodynamically stable, internal nanostructure, and offer the potential to develop a sustained drug release matrix.

The main reason behind lipid-based liquid crystals gaining a lot of interest in recent years is the fact. The delivery system utilized the advantages of lyotropic liquid crystals (LLC) creating an adaptable system that offers a variety of options for the field of transdermal delivery.

A liquid crystalline mesophase is called lyotropic (a portmanteau of lyo-"dissolve" and -tropic "change") if formed by dissolving an amphiphilic mesogen in a suitable solvent, under appropriate conditions of concentration, temperature and pressure.

A mixture of soap and water is an everyday example of a lyotropic liquid crystal. Historically, the term was used to describe the common.

His research focuses on self-assembly processes in liquid crystalline polymers, supramolecular polymers, lyotropic liquid crystals, and biological and food colloidal systems.

He is a recipient of several international awards in the field of soft condensed matter, including the John H. Dillon Medal of the American Physical Society. Negrini R, Mezzenga R () pH-responsive lyotropic liquid crystals for controlled drug delivery.

Langmuir – CrossRef PubMed Google Scholar Negrini R, Mezzenga R () Diffusion, molecular separation, and drug delivery from lipid mesophases with tunable water channels.

Liquid crystals are an emerging class of drug delivery systems made of polar lipids able to spontaneously reorganize themselves into three-dimensional structures (namely liquid. Lyotropic Surfactant Liquid Crystals.

Claire E. Fairhurst. Search for more papers by this author. Book Author(s): Prof. Demus. From conventional towards new – natural surfactants in drug delivery systems design: current status and perspectives, Expert Opinion on Drug Delivery, /, 7. Liquid Crystal Systems in Drug Delivery: /ch Liquid crystals have been recently studied as novel drug delivery system.

The reason behind this is their similarity to colloidal systems in living organisms. Drug discovery today Lyotropic liquid crystal systems in drug delivery.

[Chenyu Guo, Jun Wang, Fengliang Cao, Robert J Lee, Guangxi Zhai] PMID   Liquid crystal (LC) dosage forms, particularly those using lipid-based lyotropic LCs (LLCs), have generated considerable interest as potential drug delivery systems. LCs have the physical properties of liquids but retain some of the structural characteristics of crystalline solids.

Drug Discov Today. Dec;15() doi: / Epub Oct 8. Lyotropic liquid crystal systems in drug delivery. Self-assembled lyotropic liquid crystals GMO) and phytantriol were particularly well studied in drug delivery systems, food products, and encapsulation and crystallization of proteins.

We are summarizing in this chapter our contribution to modified LLCs and their structural features and recent systematic efforts to utilize them for. Self-Assembled Supramolecular Architectures: Lyotropic Liquid Crystals (Wiley Series on Surface and Interfacial Chemistry Book 3) - Kindle edition by Garti, Nissim, Somasundaran, Ponisseril, Mezzenga, Raffaele.

Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Self-Assembled Reviews: 1. Liquid crystalline properties are also present in mixtures of amphiphilic molecules and solvents, or shape-anisotropic colloids in solvents, which constitute the family of lyotropic liquid crystals.

These have attracted a great deal of interest in recent years, despite the fact that technological applications of these materials are not widespread.

Abstract The formation of lyotropic mesophases (liquid crystals) in four binary systems n-alkyl glycosides/water was examined in dependence on surfactant concentration, temperature and the chain lengths (alkyl = heptyl, octyl, nonyl, decyl).

The binary phase diagrams were established and the enthalpies of phase transitions were measured. The following phase transitions were detected by. Liquid crystal templating is a versatile technique to create novel organic and inorganic materials with nanoscale features.

It exploits the self-assembled architectures of liquid crystal phases as scaffolds. This article focuses on some of the key developments in lyotropic and thermotropic liquid crystals templating.

The procedures that were employed to create templated structures and the. Recent Developments in Lyotropic Liquid Crystals as Drug Delivery Vehicles Dima Libster, Abraham Aserin, and Nissim Garti. Stimuli-Responsive Lipid-Based Self-Assembled Systems Ben J. Boyd and Wye-Khay Fong.

Nonlamellar Lipid Liquid Crystalline Structures at Interfaces Debby P. Chang and Tommy Nylander. Lipids have been widely used as main constituents in various drug delivery systems, such as liposomes, solid lipid nanoparticles, nanostructured lipid carriers, and lipid-based lyotropic liquid crystals.

Among them, lipid-based lyotropic liquid crystals have highly ordered, thermodynamically stable internal nanostructure, thereby offering the potential as a sustained drug release matrix.

Video abstract of a review paper “Oral and transdermal drug delivery systems: role of lipid-based lyotropic liquid crystals” published in the open access journal Drug .Drug delivery based on LCs is a vast field of research. In recent years there has been a huge leap in interest into using LCs, particularly lyotropic liquid crystals (LLCs), as nanoparticles (cubosomes and hexosomes) for drug delivery applications.A liquid crystal is a substance that flows like a liquid but has some degree of ordering in the arrangement of its molecules.

There are three major types of liquid crystals: Thermotropic, Lyotropic, Metallotropic. Light Polymers is the expert in Lyotropic Liquid Crystals (LLCs).